The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (http://rgd.mcw.edu/contact/index.shtml).
The series of molecular signals initiated by a ligand such as a bacterial lipoprotein or peptide binding to a cotranslationally formed heterodimeric TLR1:TLR2 complex, followed by transmission of the signal by the activated receptor, and ending with the regulation of a downstream cellular process, e.g. transcription.
Synonyms:
related_synonym:
Toll Like Receptor TLR1:TLR2 Cascade; toll-like receptor TLR1:TLR2 signaling pathway